2adaptyvOfficialA- · 68Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing, thermostability measurements, enzyme activity assays, or protein sequence optimization. Also use for submitting experiments via API, tracking experiment status, downloading results, optimizing protein sequences for better expression using computational tools (NetSolP, SoluProt, SolubleMPNN, ESM), or managing protein design workflows with wet-lab validation.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 151bio-molecular-ioOfficialS · 99Reads, writes, and converts molecular file formats (SMILES, SDF, MOL2, PDB) using RDKit and Open Babel. Handles structure parsing, canonicalization, and full standardization pipeline including sanitization, normalization, and tautomer canonicalization. Use when loading chemical libraries, converting formats, or preparing molecules for analysis.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 244biologist-analystOfficialA+ · 98Analyzes living systems and biological phenomena through biological lens using evolution, molecular biology,
ecology, and systems biology frameworks.
Provides insights on mechanisms, adaptations, interactions, and life processes.
Use when: Biological systems, health issues, evolutionary questions, ecological problems, biotechnology.
Evaluates: Function, structure, heredity, evolution, interactions, molecular mechanisms.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 247biopythonOfficialA+ · 90Primary Python toolkit for molecular biology. Preferred for Python-based PubMed/NCBI queries (Bio.Entrez), sequence manipulation, file parsing (FASTA, GenBank, FASTQ, PDB), advanced BLAST workflows, structures, phylogenetics. For quick BLAST, use gget. For direct REST API, use pubmed-database.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 257chemist-analystOfficialA · 78Analyzes events through chemistry lens using molecular structure, reaction mechanisms, thermodynamics,
kinetics, and analytical techniques (spectroscopy, chromatography, mass spectrometry).
Provides insights on chemical processes, material properties, reaction pathways, synthesis, and analytical methods.
Use when: Chemical reactions, material analysis, synthesis planning, process optimization, environmental chemistry.
Evaluates: Molecular structure, reaction mechanisms, yield, selectivity, safety, environmental impact.ResearchFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 264clinical-reportsOfficialB+ · 56Write comprehensive clinical reports including case reports (CARE guidelines), diagnostic reports (radiology/pathology/lab), clinical trial reports (ICH-E3, SAE, CSR), and patient documentation (SOAP, H&P, discharge summaries). Full support with templates, regulatory compliance (HIPAA, FDA, ICH-GCP), and validation tools.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 274crisis-detection-intervention-aiOfficialB- · 31Detect crisis signals in user content using NLP, mental health sentiment analysis, and safe intervention protocols. Implements suicide ideation detection, automated escalation, and crisis resource integration. Use for mental health apps, recovery platforms, support communities. Activate on "crisis detection", "suicide prevention", "mental health NLP", "intervention protocol". NOT for general sentiment analysis, medical diagnosis, or replacing professional help.Support & Service ManagementFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 280datacommons-clientOfficialA · 79Work with Data Commons, a platform providing programmatic access to public statistical data from global sources. Use this skill when working with demographic data, economic indicators, health statistics, environmental data, or any public datasets available through Data Commons. Applicable for querying population statistics, GDP figures, unemployment rates, disease prevalence, geographic entity resolution, and exploring relationships between statistical entities.Data PlatformsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 282deep-researchOfficialS · 99Execute autonomous multi-step deep research on any topic. Use when the user asks for comprehensive research, literature reviews, competitive analysis, topic deep-dives, or wants to understand a complex subject from multiple angles. Triggers on "deep research", "research on", "investigate", "literature review", "comprehensive analysis", "what do we know about", "summarize research on".ResearchFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 292docxOfficialB- · 27Use this skill whenever the user wants to create, read, edit, or manipulate Word documents (.docx files). Triggers include: any mention of 'Word doc', 'word document', '.docx', or requests to produce professional documents with formatting like tables of contents, headings, page numbers, or letterheads. Also use when extracting or reorganizing content from .docx files, inserting or replacing images in documents, performing find-and-replace in Word files, working with tracked changes or comments, or converting content into a polished Word document. If the user asks for a 'report', 'memo', 'letter', 'template', or similar deliverable as a Word or .docx file, use this skill. Do NOT use for PDFs, spreadsheets, Google Docs, or general coding tasks unrelated to document generation.Workplace & ProductivityFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 296drugbank-databaseOfficialA+ · 95Access and analyze comprehensive drug information from the DrugBank database including drug properties, interactions, targets, pathways, chemical structures, and pharmacology data. This skill should be used when working with pharmaceutical data, drug discovery research, pharmacology studies, drug-drug interaction analysis, target identification, chemical similarity searches, ADMET predictions, or any task requiring detailed drug and drug target information from DrugBank.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 301epidemiologist-analystOfficialB · 49Analyzes disease patterns and health events through epidemiological lens using surveillance systems,
outbreak investigation methods, and disease modeling frameworks.
Provides insights on disease spread, risk factors, prevention strategies, and public health interventions.
Use when: Disease outbreaks, health policy evaluation, risk assessment, intervention planning.
Evaluates: Transmission dynamics, risk factors, causality, population health impact, intervention effectiveness.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 306exploratory-data-analysisOfficialA+ · 88Perform comprehensive exploratory data analysis on scientific data files across 200+ file formats. This skill should be used when analyzing any scientific data file to understand its structure, content, quality, and characteristics. Automatically detects file type and generates detailed markdown reports with format-specific analysis, quality metrics, and downstream analysis recommendations. Covers chemistry, bioinformatics, microscopy, spectroscopy, proteomics, metabolomics, and general scientific data formats.Data Science ToolsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 319geopandasOfficialA · 79Python library for working with geospatial vector data including shapefiles, GeoJSON, and GeoPackage files. Use when working with geographic data for spatial analysis, geometric operations, coordinate transformations, spatial joins, overlay operations, choropleth mapping, or any task involving reading/writing/analyzing vector geographic data. Supports PostGIS databases, interactive maps, and integration with matplotlib/folium/cartopy. Use for tasks like buffer analysis, spatial joins between datasets, dissolving boundaries, clipping data, calculating areas/distances, reprojecting coordinate systems, creating maps, or converting between spatial file formats.Location ServicesFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 334hrv-alexithymia-expertOfficialA · 75Heart rate variability biometrics and emotional awareness training. Expert in HRV analysis, interoception training, biofeedback, and emotional intelligence. Activate on 'HRV', 'heart rate variability', 'alexithymia', 'biofeedback', 'vagal tone', 'interoception', 'RMSSD', 'autonomic nervous system'. NOT for general fitness tracking without HRV focus, simple heart rate monitoring, or diagnosing medical conditions (only licensed professionals diagnose).Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 338interpro-databaseOfficialA · 79Query InterPro for protein family, domain, and functional site annotations. Integrates Pfam, PANTHER, PRINTS, SMART, SUPERFAMILY, and 11 other member databases. Use for protein function prediction, domain architecture analysis, evolutionary classification, and GO term mapping.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 340iso-13485-certificationOfficialA+ · 96Comprehensive toolkit for preparing ISO 13485 certification documentation for medical device Quality Management Systems. Use when users need help with ISO 13485 QMS documentation, including (1) conducting gap analysis of existing documentation, (2) creating Quality Manuals, (3) developing required procedures and work instructions, (4) preparing Medical Device Files, (5) understanding ISO 13485 requirements, or (6) identifying missing documentation for medical device certification. Also use when users mention medical device regulations, QMS certification, FDA QMSR, EU MDR, or need help with quality system documentation.LegalFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 342jungian-psychologistOfficialA+ · 93Expert in Jungian analytical psychology, depth psychology, shadow work, archetypal analysis, dream interpretation, active imagination, addiction/recovery through Jungian lens, and the individuation process - grounded in primary sources and clinical frameworks. Activate on 'Jung', 'Jungian', 'shadow work', 'archetypes', 'dream interpretation', 'active imagination', 'individuation', 'anima', 'animus', 'collective unconscious', 'addiction', 'recovery', 'spiritus contra spiritum'. NOT for therapy or diagnosis (only licensed analysts diagnose), active psychosis, severe dissociation, or replacing the relational container of actual Jungian analysis.Spirituality & EsotericaFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 346lamindbOfficialA+ · 90This skill should be used when working with LaminDB, an open-source data framework for biology that makes data queryable, traceable, reproducible, and FAIR. Use when managing biological datasets (scRNA-seq, spatial, flow cytometry, etc.), tracking computational workflows, curating and validating data with biological ontologies, building data lakehouses, or ensuring data lineage and reproducibility in biological research. Covers data management, annotation, ontologies (genes, cell types, diseases, tissues), schema validation, integrations with workflow managers (Nextflow, Snakemake) and MLOps platforms (W&B, MLflow), and deployment strategies.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 351literature-reviewOfficialA- · 71Conduct comprehensive, systematic literature reviews using multiple academic databases (PubMed, arXiv, bioRxiv, Semantic Scholar, etc.). This skill should be used when conducting systematic literature reviews, meta-analyses, research synthesis, or comprehensive literature searches across biomedical, scientific, and technical domains. Creates professionally formatted markdown documents and PDFs with verified citations in multiple citation styles (APA, Nature, Vancouver, etc.).ResearchFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 353lobster-bioinformaticsOfficialA+ · 95Run bioinformatics analyses using Lobster AI - single-cell RNA-seq, bulk RNA-seq, literature mining, dataset discovery, quality control, and visualization. Use when analyzing genomics data, searching for papers/datasets, or working with H5AD, CSV, GEO/SRA accessions, or biological data. Requires lobster-ai package installed.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 354markitdownOfficialB · 41Convert files and office documents to Markdown. Supports PDF, DOCX, PPTX, XLSX, images (with OCR), audio (with transcription), HTML, CSV, JSON, XML, ZIP, YouTube URLs, EPubs and more.Workplace & ProductivityFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 361medical-imaging-reviewOfficialS · 99Write comprehensive literature reviews for medical imaging AI research. Use when writing survey papers, systematic reviews, or literature analyses on topics like segmentation, detection, classification in CT, MRI, X-ray, ultrasound, or pathology imaging. Triggers on requests for "review paper", "survey", "literature review", "综述", "systematic review", or mentions of writing academic reviews on deep learning for medical imaging.ResearchFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 362medical-research-toolkitOfficialB+ · 57Query 14+ biomedical databases for drug repurposing, target discovery, clinical trials, and literature research. Access ChEMBL, PubMed, ClinicalTrials.gov, OpenTargets, OpenFDA, OMIM, Reactome, KEGG, UniProt, and more through a unified MCP endpoint. Use when researching disease targets, finding approved/investigational drugs, searching clinical evidence, discovering genetic associations, or analyzing compound bioactivity data.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 367modern-drug-rehab-computerOfficialS · 99Comprehensive knowledge system for addiction recovery environments, supporting both residential and outpatient (IOP/PHP) patients. Expert in evidence-based treatment modalities (CBT, DBT, MI, EMDR, MAT), recovery resources, coping strategies, crisis intervention, family systems, and holistic wellness. Activate on "rehab", "addiction recovery", "substance abuse", "treatment center", "IOP", "PHP", "detox", "sobriety support", "MAT", "Suboxone", "methadone", "12 step", "SMART Recovery". NOT for prescribing medications (consult medical professionals), emergency overdose situations (call 911), or replacing licensed counselors/therapists.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 372networkxOfficialB · 49Comprehensive toolkit for creating, analyzing, and visualizing complex networks and graphs in Python. Use when working with network/graph data structures, analyzing relationships between entities, computing graph algorithms (shortest paths, centrality, clustering), detecting communities, generating synthetic networks, or visualizing network topologies. Applicable to social networks, biological networks, transportation systems, citation networks, and any domain involving pairwise relationships.Data Science ToolsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 373neurokit2OfficialA · 79Comprehensive biosignal processing toolkit for analyzing physiological data including ECG, EEG, EDA, RSP, PPG, EMG, and EOG signals. Use this skill when processing cardiovascular signals, brain activity, electrodermal responses, respiratory patterns, muscle activity, or eye movements. Applicable for heart rate variability analysis, event-related potentials, complexity measures, autonomic nervous system assessment, psychophysiology research, and multi-modal physiological signal integration.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 380ontology-explorerOfficialC · 12Parse, navigate, and query materials science ontology structure (classes, properties, hierarchy). Use when exploring an ontology like CMSO, understanding class relationships, finding properties for a given class, or searching for ontology terms related to a materials science concept. Supports OWL/XML format from the OCDO ecosystem (CMSO, ASMO, CDCO, PODO, PLDO, LDO).ResearchFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 381open-notebookOfficialC · 0Self-hosted, open-source alternative to Google NotebookLM for AI-powered research and document analysis. Use when organizing research materials into notebooks, ingesting diverse content sources (PDFs, videos, audio, web pages, Office documents), generating AI-powered notes and summaries, creating multi-speaker podcasts from research, chatting with documents using context-aware AI, searching across materials with full-text and vector search, or running custom content transformations. Supports 16+ AI providers including OpenAI, Anthropic, Google, Ollama, Groq, and Mistral with complete data privacy through self-hosting.ResearchFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 389pathmlOfficialC+ · 14Computational pathology toolkit for analyzing whole-slide images (WSI) and multiparametric imaging data. Use this skill when working with histopathology slides, H&E stained images, multiplex immunofluorescence (CODEX, Vectra), spatial proteomics, nucleus detection/segmentation, tissue graph construction, or training ML models on pathology data. Supports 160+ slide formats including Aperio SVS, NDPI, DICOM, OME-TIFF for digital pathology workflows.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 394pdfOfficialA · 79Use this skill whenever the user wants to do anything with PDF files. This includes reading or extracting text/tables from PDFs, combining or merging multiple PDFs into one, splitting PDFs apart, rotating pages, adding watermarks, creating new PDFs, filling PDF forms, encrypting/decrypting PDFs, extracting images, and OCR on scanned PDFs to make them searchable. If the user mentions a .pdf file or asks to produce one, use this skill.Workplace & ProductivityFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 404pptxOfficialB · 42Use this skill any time a .pptx file is involved in any way — as input, output, or both. This includes: creating slide decks, pitch decks, or presentations; reading, parsing, or extracting text from any .pptx file (even if the extracted content will be used elsewhere, like in an email or summary); editing, modifying, or updating existing presentations; combining or splitting slide files; working with templates, layouts, speaker notes, or comments. Trigger whenever the user mentions "deck," "slides," "presentation," or references a .pptx filename, regardless of what they plan to do with the content afterward. If a .pptx file needs to be opened, created, or touched, use this skill.Workplace & ProductivityFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 409protein-qcOfficialA · 79Quality control metrics and filtering thresholds for protein design. Use this skill when: (1) Evaluating design quality for binding, expression, or structure, (2) Setting filtering thresholds for pLDDT, ipTM, PAE, (3) Checking sequence liabilities (cysteines, deamidation, polybasic clusters), (4) Creating multi-stage filtering pipelines, (5) Computing PyRosetta interface metrics (dG, SC, dSASA), (6) Checking biophysical properties (instability, GRAVY, pI), (7) Ranking designs with composite scoring.
This skill provides research-backed thresholds from binder design competitions and published benchmarks.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 411psychologist-analystOfficialA+ · 98Analyzes events through psychological lens using cognitive psychology, social psychology, developmental psychology,
clinical psychology, and neuroscience. Provides insights on behavior, cognition, emotion, motivation, group dynamics,
decision-making biases, mental health, and individual differences.
Use when: Behavioral patterns, decision-making, group behavior, mental health, leadership, persuasion, trauma, development.
Evaluates: Cognitive processes, emotional responses, motivations, biases, group dynamics, personality, mental states.ResearchFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 416pydicomOfficialA- · 71Python library for working with DICOM (Digital Imaging and Communications in Medicine) files. Use this skill when reading, writing, or modifying medical imaging data in DICOM format, extracting pixel data from medical images (CT, MRI, X-ray, ultrasound), anonymizing DICOM files, working with DICOM metadata and tags, converting DICOM images to other formats, handling compressed DICOM data, or processing medical imaging datasets. Applies to tasks involving medical image analysis, PACS systems, radiology workflows, and healthcare imaging applications.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 417pyhealthOfficialA · 79Comprehensive healthcare AI toolkit for developing, testing, and deploying machine learning models with clinical data. This skill should be used when working with electronic health records (EHR), clinical prediction tasks (mortality, readmission, drug recommendation), medical coding systems (ICD, NDC, ATC), physiological signals (EEG, ECG), healthcare datasets (MIMIC-III/IV, eICU, OMOP), or implementing deep learning models for healthcare applications (RETAIN, SafeDrug, Transformer, GNN).Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 418pylabrobotOfficialS · 99Laboratory automation toolkit for controlling liquid handlers, plate readers, pumps, heater shakers, incubators, centrifuges, and analytical equipment. Use this skill when automating laboratory workflows, programming liquid handling robots (Hamilton STAR, Opentrons OT-2, Tecan EVO), integrating lab equipment, managing deck layouts and resources (plates, tips, containers), reading plates, or creating reproducible laboratory protocols. Applicable for both simulated protocols and physical hardware control.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 421pyopenmsOfficialS · 99Python interface to OpenMS for mass spectrometry data analysis. Use for LC-MS/MS proteomics and metabolomics workflows including file handling (mzML, mzXML, mzTab, FASTA, pepXML, protXML, mzIdentML), signal processing, feature detection, peptide identification, and quantitative analysis. Apply when working with mass spectrometry data, analyzing proteomics experiments, or processing metabolomics datasets.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 425pyzoteroOfficialA- · 72Interact with Zotero reference management libraries using the pyzotero Python client. Retrieve, create, update, and delete items, collections, tags, and attachments via the Zotero Web API v3. Use this skill when working with Zotero libraries programmatically, managing bibliographic references, exporting citations, searching library contents, uploading PDF attachments, or building research automation workflows that integrate with Zotero.ResearchFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 426rdkitOfficialS · 99Cheminformatics toolkit for fine-grained molecular control. SMILES/SDF parsing, descriptors (MW, LogP, TPSA), fingerprints, substructure search, 2D/3D generation, similarity, reactions. For standard workflows with simpler interface, use datamol (wrapper around RDKit). Use rdkit for advanced control, custom sanitization, specialized algorithms.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 437scientific-problem-selectionOfficialA+ · 95This skill should be used when scientists need help with research problem selection, project ideation, troubleshooting stuck projects, or strategic scientific decisions. Use this skill when users ask to pitch a new research idea, work through a project problem, evaluate project risks, plan research strategy, navigate decision trees, or get help choosing what scientific problem to work on. Typical requests include "I have an idea for a project", "I'm stuck on my research", "help me evaluate this project", "what should I work on", or "I need strategic advice about my research".ResearchFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 442scikit-learnOfficialA · 79Machine learning in Python with scikit-learn. Use when working with supervised learning (classification, regression), unsupervised learning (clustering, dimensionality reduction), model evaluation, hyperparameter tuning, preprocessing, or building ML pipelines. Provides comprehensive reference documentation for algorithms, preprocessing techniques, pipelines, and best practices.Data Science ToolsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 446scvi-toolsOfficialS · 99This skill should be used when working with single-cell omics data analysis using scvi-tools, including scRNA-seq, scATAC-seq, CITE-seq, spatial transcriptomics, and other single-cell modalities. Use this skill for probabilistic modeling, batch correction, dimensionality reduction, differential expression, cell type annotation, multimodal integration, and spatial analysis tasks.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 449shapOfficialA+ · 95Model interpretability and explainability using SHAP (SHapley Additive exPlanations). Use this skill when explaining machine learning model predictions, computing feature importance, generating SHAP plots (waterfall, beeswarm, bar, scatter, force, heatmap), debugging models, analyzing model bias or fairness, comparing models, or implementing explainable AI. Works with tree-based models (XGBoost, LightGBM, Random Forest), deep learning (TensorFlow, PyTorch), linear models, and any black-box model.Data Science ToolsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 458speech-pathology-aiOfficialC · 9Expert speech-language pathologist specializing in AI-powered speech therapy, phoneme analysis, articulation visualization, voice disorders, fluency intervention, and assistive communication technology. Activate on 'speech therapy', 'articulation', 'phoneme analysis', 'voice disorder', 'fluency', 'stuttering', 'AAC', 'pronunciation', 'speech recognition', 'mellifluo.us'. NOT for general audio processing, music production, or voice acting coaching without clinical context.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 472tooluniverse-cancer-variant-interpretationOfficialA+ · 97Provide comprehensive clinical interpretation of somatic mutations in cancer. Given a gene symbol + variant (e.g., EGFR L858R, BRAF V600E) and optional cancer type, performs multi-database analysis covering clinical evidence (CIViC), mutation prevalence (cBioPortal), therapeutic associations (OpenTargets, ChEMBL, FDA), resistance mechanisms, clinical trials, prognostic impact, and pathway context. Generates an evidence-graded markdown report with actionable recommendations for precision oncology. Use when oncologists, molecular tumor boards, or researchers ask about treatment options for specific cancer mutations, resistance mechanisms, or clinical trial matching.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 473tooluniverse-chemical-compound-retrievalOfficialB · 48Retrieves chemical compound information from PubChem and ChEMBL with disambiguation, cross-referencing, and quality assessment. Creates comprehensive compound profiles with identifiers, properties, bioactivity, and drug information. Use when users need chemical data, drug information, or mention PubChem CID, ChEMBL ID, SMILES, InChI, or compound names.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 474tooluniverse-chemical-safetyOfficialA+ · 97Comprehensive chemical safety and toxicology assessment integrating ADMET-AI predictions, CTD toxicogenomics, FDA label safety data, DrugBank safety profiles, and STITCH chemical-protein interactions. Performs predictive toxicology (AMES, DILI, LD50, carcinogenicity), organ/system toxicity profiling, chemical-gene-disease relationship mapping, regulatory safety extraction, and environmental hazard assessment. Use when asked about chemical toxicity, drug safety profiling, ADMET properties, environmental health risks, chemical hazard assessment, or toxicogenomic analysis.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 475tooluniverse-clinical-guidelinesOfficialS · 99Search and retrieve clinical practice guidelines across 12+ authoritative sources including NICE, WHO, ADA, AHA/ACC, NCCN, SIGN, CPIC, CMA, CTFPHC, GIN, MAGICapp, PubMed, EuropePMC, TRIP, and OpenAlex. Covers disease management, cardiology, oncology, diabetes, pharmacogenomics, and more. Use when users ask about clinical guidelines, treatment recommendations, standard of care, evidence-based medicine, or drug-gene dosing recommendations.ResearchFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 477tooluniverse-clinical-trial-matchingOfficialA · 79AI-driven patient-to-trial matching for precision medicine and oncology. Given a patient profile (disease, molecular alterations, stage, prior treatments), discovers and ranks clinical trials from ClinicalTrials.gov using multi-dimensional matching across molecular eligibility, clinical criteria, drug-biomarker alignment, evidence strength, and geographic feasibility. Produces a quantitative Trial Match Score (0-100) per trial with tiered recommendations and a comprehensive markdown report. Use when oncologists, molecular tumor boards, or patients ask about clinical trial options for specific cancer types, biomarker profiles, or post-progression scenarios.ResearchFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 478tooluniverse-crispr-screen-analysisOfficialA+ · 98Comprehensive CRISPR screen analysis for functional genomics. Analyze pooled or arrayed CRISPR screens (knockout, activation, interference) to identify essential genes, synthetic lethal interactions, and drug targets. Perform sgRNA count processing, gene-level scoring (MAGeCK, BAGEL), quality control, pathway enrichment, and drug target prioritization. Use for CRISPR screen analysis, gene essentiality studies, synthetic lethality detection, functional genomics, drug target validation, or identifying genetic vulnerabilities.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 480tooluniverse-drug-drug-interactionOfficialA+ · 97Comprehensive drug-drug interaction (DDI) prediction and risk assessment. Analyzes interaction mechanisms (CYP450, transporters, pharmacodynamic), severity classification, clinical evidence grading, and provides management strategies. Supports single drug pairs, polypharmacy analysis (3+ drugs), and alternative drug recommendations. Use when users ask about drug interactions, medication safety, polypharmacy risks, or need DDI assessment for clinical decision support.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 481tooluniverse-drug-researchOfficialA+ · 96Generates comprehensive drug research reports with compound disambiguation, evidence grading, and mandatory completeness sections. Covers identity, chemistry, pharmacology, targets, clinical trials, safety, pharmacogenomics, and ADMET properties. Use when users ask about drugs, medications, therapeutics, or need drug profiling, safety assessment, or clinical development research.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 482tooluniverse-drug-target-validationOfficialA+ · 97Comprehensive computational validation of drug targets for early-stage drug discovery. Evaluates targets across 10 dimensions (disambiguation, disease association, druggability, chemical matter, clinical precedent, safety, pathway context, validation evidence, structural insights, validation roadmap) using 60+ ToolUniverse tools. Produces a quantitative Target Validation Score (0-100) with GO/NO-GO recommendation. Use when users ask about target validation, druggability assessment, target prioritization, or "is X a good drug target for Y?"Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 483tooluniverse-epigenomicsOfficialA+ · 93Production-ready genomics and epigenomics data processing for BixBench questions. Handles methylation array analysis (CpG filtering, differential methylation, age-related CpG detection, chromosome-level density), ChIP-seq peak analysis (peak calling, motif enrichment, coverage stats), ATAC-seq chromatin accessibility, multi-omics integration (expression + methylation correlation), and genome-wide statistics. Pure Python computation (pandas, scipy, numpy, pysam, statsmodels) plus ToolUniverse annotation tools (Ensembl, ENCODE, SCREEN, JASPAR, ReMap, RegulomeDB, ChIPAtlas). Supports BED, BigWig, methylation beta-value matrices, Illumina manifest files, and multi-sample clinical data. Use when processing methylation data, ChIP-seq peaks, ATAC-seq signals, or answering questions about CpG sites, differential methylation, chromatin accessibility, histone marks, or epigenomic statistics.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 490tooluniverse-image-analysisOfficialB+ · 55Production-ready microscopy image analysis and quantitative imaging data skill for colony morphometry, cell counting, fluorescence quantification, and statistical analysis of imaging-derived measurements. Processes ImageJ/CellProfiler output (area, circularity, intensity, cell counts), performs Dunnett's test, Cohen's d effect size, power analysis, Shapiro-Wilk normality tests, two-way ANOVA, polynomial regression, natural spline regression with confidence intervals, and comparative morphometry. Supports CSV/TSV measurement tables, multi-channel fluorescence data, colony swarming assays, and neuron counting datasets. Use when analyzing microscopy measurement data, colony area/circularity, cell count statistics, swarming assays, co-culture ratio optimization, or answering questions about imaging-derived quantitative data.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 492tooluniverse-immunotherapy-response-predictionOfficialA+ · 97Predict patient response to immune checkpoint inhibitors (ICIs) using multi-biomarker integration. Given a cancer type, somatic mutations, and optional biomarkers (TMB, PD-L1, MSI status), performs systematic analysis across 11 phases covering TMB classification, neoantigen burden estimation, MSI/MMR assessment, PD-L1 evaluation, immune microenvironment profiling, mutation-based resistance/sensitivity prediction, clinical evidence retrieval, and multi-biomarker score integration. Generates a quantitative ICI Response Score (0-100), response likelihood tier, specific ICI drug recommendations with evidence, resistance risk factors, and a monitoring plan. Use when oncologists ask about immunotherapy eligibility, checkpoint inhibitor selection, or biomarker-guided ICI treatment decisions.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 494tooluniverse-literature-deep-researchOfficialA+ · 98Conduct comprehensive literature research with target disambiguation, evidence grading, and structured theme extraction. Creates a detailed report with mandatory completeness checklist, biological model synthesis, and testable hypotheses. For biological targets, resolves official IDs (Ensembl/UniProt), synonyms, naming collisions, and gathers expression/pathway context before literature search. Default deliverable is a report file; for single factoid questions, uses a fast verification mode and may include an inline answer. Use when users need thorough literature reviews, target profiles, or to verify specific claims from the literature.ResearchFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 495tooluniverse-metabolomicsOfficialA · 75Comprehensive metabolomics research skill for identifying metabolites, analyzing studies, and searching metabolomics databases. Integrates HMDB (220k+ metabolites), MetaboLights, Metabolomics Workbench, and PubChem. Use when asked to identify or annotate metabolites (HMDB IDs, chemical properties, pathways), retrieve metabolomics study information from MetaboLights (MTBLS*) or Metabolomics Workbench (ST*), search for studies by keywords or disease, or generate comprehensive metabolomics research reports.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 496tooluniverse-metabolomics-analysisOfficialS · 99Analyze metabolomics data including metabolite identification, quantification, pathway analysis, and metabolic flux. Processes LC-MS, GC-MS, NMR data from targeted and untargeted experiments. Performs normalization, statistical analysis, pathway enrichment, metabolite-enzyme integration, and biomarker discovery. Use when analyzing metabolomics datasets, identifying differential metabolites, studying metabolic pathways, integrating with transcriptomics/proteomics, discovering metabolic biomarkers, performing flux balance analysis, or characterizing metabolic phenotypes in disease, drug response, or physiological conditions.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 497tooluniverse-multi-omics-integrationOfficialS · 99Integrate and analyze multiple omics datasets (transcriptomics, proteomics, epigenomics, genomics, metabolomics) for systems biology and precision medicine. Performs cross-omics correlation, multi-omics clustering (MOFA+, NMF), pathway-level integration, and sample matching. Coordinates ToolUniverse skills for expression data (RNA-seq), epigenomics (methylation, ChIP-seq), variants (SNVs, CNVs), protein interactions, and pathway enrichment. Use when analyzing multi-omics datasets, performing integrative analysis, discovering multi-omics biomarkers, studying disease mechanisms across molecular layers, or conducting systems biology research that requires coordinated analysis of transcriptome, genome, epigenome, proteome, and metabolome data.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 498tooluniverse-multiomic-disease-characterizationOfficialA · 79Comprehensive multi-omics disease characterization integrating genomics, transcriptomics, proteomics, pathway, and therapeutic layers for systems-level understanding. Produces a detailed multi-omics report with quantitative confidence scoring (0-100), cross-layer gene concordance analysis, biomarker candidates, therapeutic opportunities, and mechanistic hypotheses. Uses 80+ ToolUniverse tools across 8 analysis layers. Use when users ask about disease mechanisms, multi-omics analysis, systems biology of disease, biomarker discovery, or therapeutic target identification from a disease perspective.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 500tooluniverse-phylogeneticsOfficialA+ · 89Production-ready phylogenetics and sequence analysis skill for alignment processing, tree analysis, and evolutionary metrics. Computes treeness, RCV, treeness/RCV, parsimony informative sites, evolutionary rate, DVMC, tree length, alignment gap statistics, GC content, and bootstrap support using PhyKIT, Biopython, and DendroPy. Performs NJ/UPGMA/parsimony tree construction, Robinson-Foulds distance, Mann-Whitney U tests, and batch analysis across gene families. Integrates with ToolUniverse for sequence retrieval (NCBI, UniProt, Ensembl) and tree annotation. Use when processing FASTA/PHYLIP/Nexus/Newick files, computing phylogenetic metrics, comparing taxa groups, or answering questions about alignments, trees, parsimony, or molecular evolution.Biology Medicine and BioinformaticsFreedomIntelligence/OpenClaw-Medical-Skills · 0 installsFreedomIntelligence/OpenClaw-Medical-Skills0 