drug-discovery-search

FreedomIntelligence/OpenClaw-Medical-SkillsBiology Medicine and BioinformaticsAudit pendingSnapshot d64ed892ee68

Summary

This source did not publish a separate summary. Review SKILL.md before using the skill.

SKILL.md

Drug Discovery Search

Search across all major drug discovery databases (ChEMBL, DrugBank, FDA drug labels, Open Targets) simultaneously using natural language queries powered by Valyu's semantic search API.

Why This Skill is Powerful

No API Parameter Parsing: Just pass natural language queries directly - no need to construct complex search parameters
Semantic Search: Understands the meaning of your query, not just keyword matching
Full-Text Access: Returns complete compound, target, and drug information
Image Links: Includes molecular structures and data visualizations
Comprehensive Coverage: Search across ChEMBL, DrugBank, drug labels, and Open Targets simultaneously
Unified Results: Get results from all drug discovery sources in a single query

Requirements

Node.js 18+ (uses built-in fetch)
Valyu API key from https://platform.valyu.ai ($10 free credits)

CRITICAL: Script Path Resolution

The scripts/search commands in this documentation are relative to this skill's installation directory.

Before running any command, locate the script using:

DRUG_DISCOVERY_SCRIPT=$(find ~/.claude/plugins/cache -name "search" -path "*/drug-discovery-search/*/scripts/*" -type f 2>/dev/null | head -1)

Then use the full path for all commands:

$DRUG_DISCOVERY_SCRIPT "JAK2 inhibitors" 20

API Key Setup Flow

When you run a search and receive "setup_required": true, follow this flow:

Ask the user for their API key: "To search drug discovery databases, I need your Valyu API key. Get one free ($10 credits) at https://platform.valyu.ai"

{
  "success": true,
  "type": "drug_discovery_search",
  "query": "JAK2 inhibitors",
  "result_count": 20,
  "results": [
    {
      "title": "Compound/Drug/Target Title",
      "url": "https://...",
      "content": "Full data including compounds, targets, mechanisms...",
      "source": "chembl|drugbank|drug-labels|open-targets",
      "relevance_score": 0.95,
      "images": ["https://example.com/structure.png"]
    }
  ],
  "cost": 0.035
}

# Get titles
scripts/search "query" 20 | jq -r '.results[].title'

# Get URLs
scripts/search "query" 20 | jq -r '.results[].url'

# Extract full content
scripts/search "query" 20 | jq -r '.results[].content'

# Filter by source
scripts/search "query" 20 | jq -r '.results[] | select(.source == "chembl") | .title'

# Find validated targets and compounds
scripts/search "BTK inhibitors for autoimmune diseases" 50

# Search SAR and compound data
scripts/search "EGFR inhibitors blood-brain barrier penetration" 40

# Find repurposing opportunities
scripts/search "mTOR inhibitors cancer and aging" 30

# Gather safety and interaction data
scripts/search "tyrosine kinase inhibitors cardiac toxicity" 60

{
  "success": false,
  "error": "Error message"
}

scripts/
├── search          # Bash wrapper
└── search.mjs      # Node.js CLI

from valyu import Valyu

client = Valyu(api_key="your-api-key")

response = client.search(
    query="your search query here",
    included_sources=["valyu/valyu-chembl", "valyu/valyu-drugbank", "valyu/valyu-drug-labels", "valyu/valyu-open-targets"],
    max_results=20
)

for result in response["results"]:
    print(f"Title: {result['title']}")
    print(f"URL: {result['url']}")
    print(f"Content: {result['content'][:500]}...")

import { Valyu } from "valyu-js";

const client = new Valyu("your-api-key");

const response = await client.search({
  query: "your search query here",
  includedSources: ["valyu/valyu-chembl", "valyu/valyu-drugbank", "valyu/valyu-drug-labels", "valyu/valyu-open-targets"],
  maxResults: 20
});

response.results.forEach((result) => {
  console.log(`Title: ${result.title}`);
  console.log(`URL: ${result.url}`);
  console.log(`Content: ${result.content.substring(0, 500)}...`);
});

drug-discovery-search

Summary

SKILL.md

Drug Discovery Search

Why This Skill is Powerful

Requirements

CRITICAL: Script Path Resolution

API Key Setup Flow

When to Use This Skill

Output Format

Processing Results

With jq

Common Use Cases

Target Identification

Lead Optimization

Drug Repurposing

Safety Assessment

Error Handling

API Endpoint

Architecture

Adding to Your Project

Python Integration

TypeScript Integration

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