BioCosm

Installation

Use an MCP-capable client and connect to the remote BioCosm endpoint at https://biocosm-mcp.fly.dev/mcp.

Claude Code setup:

claude mcp add --transport http biocosm-io https://biocosm-mcp.fly.dev/mcp

For local inspection, the official MCP inspector can be started with:

npx @modelcontextprotocol/inspector

Configuration

• Remote transport: streamable-http
• Endpoint: https://biocosm-mcp.fly.dev/mcp
• Authentication: none documented
• No public source repository or source code was found during review; this submission is based on the public BioCosm site and MCP documentation.

Capabilities

BioCosm provides biomedical knowledge retrieval for drugs, diagnostics, targets, companies, and pipeline compounds.

Documented tools include:

• search_nodes
• get_node
• get_writeup
• list_by_therapeutic_area
• get_company_portfolio
• get_stats
• get_staleness_report
• get_node_freshness
• find_by_target
• find_by_phase
• find_related
• get_pos_score
• get_coverage

The site also documents probability-of-success estimates, writeups with citations, portfolio queries, and coverage/staleness reporting.

Limitations

• BioCosm is an AI-powered, automatically generated research tool; individual facts can be incomplete, out of date, or wrong.
• Coverage is uneven, and missing fields mean data was not populated in BioCosm, not that the real-world value is zero.
• Diagnostic programs are not scored.
• Combination regimens are harder to model.
• Probability estimates are not financial or medical advice.
• Pipeline status is updated periodically from ClinicalTrials.gov and FDA; primary sources should still be checked before acting on any result.
• No public source repository or source code was found for this submission.